产品货号:
LA10420
中文名称:
人β-淀粉样蛋白(1-40)
英文名称:
Amyloid β Peptide(1-40),human
产品规格:
1mg|5mg
发货周期:
1~3天
产品价格:
询价
CAS号 | 131438-79-4 |
分子式 | C194H295N53O58S |
分子量 | 4329.9 |
溶解性 | 溶于DMSO,微溶于水 |
纯度等级 | >95%,BR |
储存条件 | -20℃ |
氨基酸序列 | Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val |
Amyloid β Peptide(1-40) human is a 40-residue peptide implicated in the pathogenesis of Alzheimer's disease (AD) and aged Down's Syndrome,which is promoted by the acquisition of an additional copy of chromosome 21.The peptide is a proteolytic product of the much larger amyloid precursor protein (APP) encoded by a gene on chromosome 21.The peptide comprises a large extracellular N-terminal domain and a short hydrophobic membrane-spanning domain,followed by a short C-terminal region.Beta-APP both precedes and forms part of the transmembrane region.
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